Development of diagnostic test systems using nanoparticles for determinations of markers of ecologically significant diseases

Authors

  • Anastasia Stoinova RUDN University
  • Alexander Zubkov
  • Valentina Panchenko
  • Yaroslav Stanishevskiy

DOI:

https://doi.org/10.5755/j01.erem.74.3.21100

Keywords:

ecologically significant diseases, diagnostic test- system, silver nanoparticles, gold nanoparticles, kinetics, sonication, bionanoconjugates.

Abstract

Diseases of animals and humans are largely environmentally-related. With the timely detection of the disease, it is possible to avoid severe consequences, both for human health or for the animal, and for the environment as a whole. The article describes the process of creating diagnostic test systems, including obtaining used nanoparticles and describing their physicochemical properties as the kinetics of gold and silver nanoparticles in mono- and binary hydrosols using spectroscopic methods of investigation, determined the size of silver nanoparticles on the basis of the method of cross-correlation spectroscopy of photons and Transmission Electron Microscopy and the effect of ultrasound on the spectroscopic data hydrosols of gold and silver. The article contains a description of the technology of obtaining bionanconjugates - a key link for creating diagnostic test systems. The results of the development of diagnosticums were presented at the end of the article and the corresponding conclusions were drawn.

DOI: http://dx.doi.org/10.5755/j01.erem.74.3.21100

Author Biography

Anastasia Stoinova, RUDN University

Vice Dean of Institute of biochemical technology and nanotechnology

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Published

2018-11-06

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Section

Articles