Forecasting of Dangerous Influence of Avermectin Insecticides to Human Organism Using Surface and Groundwater for Drinking


  • Anna Antonenko Bogomolets National Medical University
  • Olena Vavrinevych
  • Bohdan Shpak
  • Sergii Omelchuk



More than 400 types of harmful organisms cause damage to agricultural crops. Insecticides occupy one of the last places in the structure of the pesticides assortment among formulations authorized for application in the world. However, they occupy the first place according to their toxicity and the hazard effect to the human body. The purpose of our study was comparative hygienic assessment of soil stability, surface and groundwater migration potential, prediction of dangerous effects of insecticides-avermectins on the human body after using surface and groundwater for drinking needs. For an integral assessment of the potential danger of pesticide exposure to the human body after consumption of water from surface and groundwater supply sources, a scale of four gradations was used. It includes the LEACH (index of potential contamination of groundwater and river waters), half-life period (DT50) in water and an allowable daily dose (ADD) or acceptable daily intake (ADI). It has been established that in different soil and climatic conditions, according to the LEACH index, there is a very low risk of groundwater and surface water contamination. This is due to their relatively high solubility in water, low soil persistence and very high values of the organic carbon sorption coefficient. According to the IIWH index (integral index of water hazard), abamectin and emamectin benzoate in different soil and climatic conditions are moderately hazardous for a person after consumption of contaminated drinking water (class 3); emamectin benzoate in the soil and climatic conditions of Ukraine is hazardous (class 2). It is necessary to monitor carefully the boundaries of sanitary-protective areas from treated areas to water bodies, and control the process of exploitation of water supply sources, especially decentralized in rural areas. In regions with intensive agricultural production, it is recommended to use the IIWH index to make a decision about the necessity of monitoring research on insecticides in water.